Systematic ReviewResearch

Maternal anemia was associated with higher odds of preterm birth

The journal of maternal-fetal & neonatal medicine (PubMed)Sep 3, 2026

AI-summarized from the linked source. Educational brief, not medical advice.

Brief summary

A meta-analysis linked maternal anemia with preterm birth, but it did not establish that anemia treatment prevents early delivery.

What NurseJet pulled from the source

The review included 45 articles covering 60 study populations and 2,119,392 pregnant individuals. The pooled odds ratio for preterm birth was 1.28 (95% CI 1.20–1.36). Between-study heterogeneity was substantial.

Why this matters for nurses

This association provides context for discussing anemia within pregnancy risk assessment.

Bedside takeaway

Use this evidence to inform discussion of maternal risk; follow the local anemia screening and treatment pathway.

Key takeaways

Heterogeneity was high (I² 95.54%).
The authors identified possible publication bias.
The findings describe an association, not an absolute risk increase or a treatment effect.

Practice implications

Use this evidence to inform discussion of maternal risk; follow the local anemia screening and treatment pathway.

Limitations & cautions

Abstract-only summary. High heterogeneity and potential publication bias limit confidence in a single pooled estimate. This review does not test a specific screening or supplementation strategy.
AI-summarized from the linked source. Review the original article before applying to practice.

Citations

Exact source links

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The journal of maternal-fetal & neonatal medicine (PubMed)

The journal of maternal-fetal & neonatal medicine (PubMed). Maternal anemia and the risk of preterm birth: a meta-analysis.

Open original source

https://pubmed.ncbi.nlm.nih.gov/42692818/

Professional education only

This summary does not replace clinical judgment, facility policy, provider orders, or official guidelines. Verify practice changes against the original source and local protocol.

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Obstetrics and gynecology (PubMed)Oct 1, 2026Systematic Review

A systematic review and meta-analysis of 30 US studies found doula support during pregnancy, childbirth, and postpartum was associated with lower rates of preterm birth and cesarean delivery, improved birth experiences, and higher postpartum visit attendance.

L&D / OB Med-SurgAI summaryReview source

Systematic ReviewResearchPatient EducationAI summary · original source linked below

Continuous non-clinical labor support has drawn increasing interest to address severe maternal health disparities and high obstetric intervention rates across the United States. This systematic review and meta-analysis evaluated 30 US-based studies (12 randomized controlled trials and 18 nonrandomized studies of interventions) examining doula care compared with standard maternity care. Using GRADE methodology, the investigators found moderate-certainty evidence that doula support is likely associated with lower rates of preterm birth, decreased cesarean delivery, improved maternal birth experiences, and higher postpartum visit attendance. Low-certainty evidence suggested potential associations with improved prenatal mood, increased spontaneous vaginal birth and vaginal birth after cesarean (VBAC), earlier breastfeeding initiation, reduced epidural analgesia use, shorter labor duration, and lower infant mortality. Doula support was not associated with reductions in hypertensive disorders of pregnancy, maternal readmissions, or NICU admissions. Notably, four of five studies focusing specifically on populations experiencing structural disparities (by race, incarceration, low income, or Medicaid insurance) documented positive maternal-infant benefits.

Key takeaways

Systematic review synthesized 12 RCTs and 18 nonrandomized studies evaluating US doula support.
Moderate-certainty evidence links doula support to lower rates of preterm birth and cesarean delivery.
Doula care was associated with improved maternal birth experience and increased postpartum appointment attendance.
Four of five studies in populations facing structural health disparities reported measurable benefits from doula collaboration.

Why this matters on shift

Labor and delivery and postpartum nurses work directly alongside doulas at the bedside to promote physiological birth, manage labor discomfort, and advocate for patient autonomy. High-level evidence validating that doula support reduces operative deliveries and bolsters postpartum follow-up reinforces collaborative, respectful interprofessional nursing practice.

Bedside takeaway

In a meta-analysis of 30 US studies, doula support was linked to lower preterm birth and cesarean rates, better birth experiences, and higher postpartum visit attendance (moderate certainty).

Nursing implications

Welcome community and hospital-based doulas into labor suites as valued members of the birth support team, coordinate non-pharmacological comfort measures collaboratively, and encourage postpartum follow-up engagement during pre-discharge teaching.

Limitations & cautions

Nineteen of the 30 included studies had high risk of bias; considerable heterogeneity was observed across clinical outcomes; data regarding the optimal timing, dose, and model of doula care were limited.
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Citations · exact source links

Obstetrics and gynecology (PubMed). Doula Support During Pregnancy, Childbirth, and Postpartum: A Systematic Review and Meta-Analysis.

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International journal of nursing studies advances (PubMed)Sep 21, 2026Systematic Review

A systematic review and meta-analysis of 17 randomized controlled trials encompassing 2,364 parent-infant dyads found that eHealth-supported early intervention programmes initiated in the NICU significantly reduced parental depressive symptoms at three months post-discharge compared with usual care.

Peds L&D / OBAI summaryReview source

Systematic ReviewResearchPatient EducationWorkflowAI summary · original source linked below

Discharge from the neonatal intensive care unit represents a highly stressful transition for parents of premature infants, often accompanied by postpartum depression, anxiety, and feelings of caregiving inadequacy. This PRISMA systematic review and meta-analysis (PROSPERO CRD42023444721) synthesized 17 randomized controlled trials involving 2,364 parent-infant dyads to determine the efficacy of eHealth-supported transitional programmes initiated during NICU hospitalization or immediately following discharge. Random-effects pooled analysis revealed a statistically significant reduction in parental depressive symptoms at three months post-discharge favoring eHealth interventions over usual care (standardized mean difference -0.25; 95% CI -0.43 to -0.08). Point estimates for parental stress, anxiety, and parenting self-efficacy also numerically favored eHealth programmes, though confidence intervals crossed the null. Data on breastfeeding continuity and infant developmental outcomes were limited across trials.

Key takeaways

Systematic review and meta-analysis synthesized 17 randomized controlled trials involving 2,364 parent-preterm infant dyads.
Evaluated eHealth transitional platforms initiated during NICU hospitalization or immediately post-discharge.
eHealth programmes produced a statistically significant reduction in parental depressive symptoms at three months (SMD -0.25; 95% CI -0.43 to -0.08).
Parental stress and anxiety point estimates favored digital support, but evidence for infant health service utilization remained limited.

Why this matters on shift

NICU and pediatric nurses play a pivotal role in preparing families for safe home discharge. Confirming that structured eHealth communication tools alleviate parental depression in the critical 3-month post-discharge window validates digital extensions of nursing transitional support for vulnerable families.

Bedside takeaway

A meta-analysis of 17 RCTs (2,364 parent-infant dyads) found nurse-led eHealth transitional support significantly reduced parental depressive symptoms at 3 months post-NICU discharge (SMD -0.25, 95% CI -0.43 to -0.08).

Nursing implications

Integrate verified eHealth or secure messaging platforms into NICU discharge education workflows to provide continuous maternal and paternal guidance, monitoring parents closely for signs of postpartum depression throughout the 90-day transitional period.

Limitations & cautions

Moderate heterogeneity across interventions (web portals, mobile apps, video consultations); wide confidence intervals for stress and anxiety outcomes; scarce reporting of infant clinical and developmental endpoints.
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Citations · exact source links

International journal of nursing studies advances (PubMed). Effectiveness of eHealth interventions for parents of preterm infants during transition from neonatal intensive care unit-to-home: A systematic review and meta-analysis.

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Midwifery (PubMed)Sep 1, 2026Systematic Review

A systematic review and meta-analysis of 13 studies found that cognitive behavioral therapy for postpartum depression significantly increased exclusive breastfeeding rates compared with usual care (RR 1.54), whereas other treatment modalities showed non-significant pooled effects.

L&D / OB PsychAI summaryReview source

Systematic ReviewResearchPatient EducationQuality ImprovementAI summary · original source linked below

Postpartum depression affects up to 25% of new mothers and frequently compromises breastfeeding duration and exclusivity. Synthesizing 13 studies (9 RCTs and 4 cohort studies) evaluating 9 distinct interventions, this meta-analysis investigated how postpartum depression treatments influence lactation outcomes. Cognitive behavioral therapy (CBT) significantly increased exclusive breastfeeding rates compared with usual care controls (RR 1.54; 95% CI 1.06-2.22). In contrast, pooled analysis of other interventions—including general mental health education, breastfeeding-targeted psychological programs, esketamine, and problem-solving therapy—showed a non-significant overall effect on exclusive breastfeeding (pooled RR 1.13; 95% CI 0.96-1.32). Interventions also demonstrated non-significant trends toward reduced lactation insufficiency (RR 0.81; 95% CI 0.65-1.01).

Key takeaways

Synthesized 13 studies (9 RCTs and 4 cohorts) evaluating 9 postpartum depression interventions across major medical databases.
Cognitive behavioral therapy produced a 54% higher exclusive breastfeeding rate compared to usual care (RR 1.54; 95% CI 1.06-2.22).
Combined meta-analysis of non-CBT interventions (including esketamine and education) showed no statistically significant boost in exclusive breastfeeding (pooled RR 1.13).
Reductions in perceived lactation insufficiency showed non-significant trends (pooled RR 0.81; 95% CI 0.65-1.01).

Why this matters on shift

Depression in the postpartum period is intimately intertwined with infant feeding challenges, guilt, and early breastfeeding cessation. Obstetric, postpartum, and lactation nurses often worry whether treating maternal depressive symptoms will negatively impact lactation. This review demonstrates that evidence-based psychotherapy (CBT) not only addresses maternal mental health, but actively supports maternal confidence and exclusive breastfeeding success.

Bedside takeaway

In mothers with postpartum depression, cognitive behavioral therapy significantly increased exclusive breastfeeding rates by 54% (RR 1.54) over usual care.

Nursing implications

Screen postpartum mothers routinely using validated instruments such as the Edinburgh Postnatal Depression Scale (EPDS). When depressive symptoms or feeding distress are detected, advocate for prompt referral to perinatal mental health professionals offering CBT, while providing reassuring, trauma-informed lactation guidance.

Limitations & cautions

Only 13 studies met inclusion criteria, with variable definitions of breastfeeding exclusivity and duration; pharmacotherapy trials reporting explicit breastfeeding metrics were limited.
AI-summarized from the linked source. Review the original article before applying to practice.

Citations · exact source links

Midwifery (PubMed). The effect of treatments for postpartum depression on breastfeeding practices: a systematic review and meta-analysis.

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AI-summarized from the linked source. Review the original article before applying to practice.

Key takeaways

Practice implications

Limitations & cautions

Exact source links

More updates for this clinical area

Systematic review and meta-analysis finds doula support linked to lower preterm birth and cesarean delivery rates

Meta-analysis of 17 RCTs finds eHealth transitional support reduces parental depressive symptoms at 3 months post-NICU discharge

Meta-analysis finds cognitive behavioral therapy for postpartum depression increases exclusive breastfeeding rates by 54%