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Key takeaways

• The review pooled 18 randomized trials involving 15,560 adults hospitalized with acute heart failure.
• Heart-failure worsening or hospitalization was lower with in-hospital SGLT2-inhibitor initiation (RR 0.77, 95% CI 0.67 to 0.88; NNT 48).
• Diuretic efficiency, weight loss, NT-proBNP, and quality-of-life scores favored initiation during hospitalization.
• No increase was detected in acute kidney injury, hypotension, hypoglycemia, ketoacidosis, genitourinary infection, or other serious adverse events.

Nursing implications

• When an SGLT2 inhibitor is prescribed during an acute-heart-failure admission, reconcile the medication, trend the ordered volume and safety measures, and make the follow-up plan visible at discharge. A pooled absence of excess adverse events does not remove patient-specific contraindications or monitoring requirements.

Limitations & cautions

• This meta-analysis pooled trial-level evidence through February 2026. The all-cause mortality signal showed potential publication bias and weakened in sensitivity analysis, several outcomes did not differ significantly, and the authors call for longer-term confirmatory data.
• AI-summarized from the linked source. Review the original article before applying to practice.

Key takeaways

• The review included 52 publications addressing precision-oncology nursing roles, competencies, or education.
• Nursing contributions extended from genomic risk assessment and communication to navigation, service integration, and governance.
• Most identified education emphasized foundational capabilities, with less explicit preparation for advanced interpretive and leadership roles.
• The proposed three-level competency model is a framework and has not been validated as an education or patient-outcome intervention.

Nursing implications

• Clarify which genomic conversations, assessments, and coordination tasks fall within the nurse's verified competency and local role. Use approved patient resources, route interpretive questions to qualified genetics or oncology clinicians, and document education and follow-up needs.

Limitations & cautions

• This was a scoping review that mapped a heterogeneous literature and education landscape rather than evaluating effectiveness. The education search included generative-AI-assisted grey-literature methods, identified program availability may change, and the proposed competency levels require validation before they are used for credentialing or scope decisions.
• AI-summarized from the linked source. Review the original article before applying to practice.

Key takeaways

• The review included 19 studies, with 14 contributing data to meta-analysis.
• Scenario-based simulation produced a moderate pooled cognitive effect and a large affective effect.
• Immediate knowledge improvement was not maintained at subsequent follow-up assessments.
• Confidence and self-efficacy benefits were sustained over time in the included evidence.

Nursing implications

• Education teams can pair scenario-based simulation with delayed knowledge checks and reinforcement rather than relying only on immediate post-training scores. Programs should assess cognitive and affective outcomes separately because the review found different patterns of durability.

Limitations & cautions

• Only 14 of the 19 included studies contributed to meta-analysis. The abstract does not report the total number of participants, between-study heterogeneity, or detailed risk-of-bias results, and the cognitive benefit was not maintained at follow-up.
• AI-summarized from the linked source. Review the original article before applying to practice.

Key takeaways

• The review included 23 studies across neonatal, pediatric intensive-care, and pediatric medical-surgical settings.
• Sixteen studies were quality-improvement projects, five were nonrandomized, and only two were randomized trials.
• Most studies reported lower alarm frequency, and all studies measuring nonactionable alarms reported decreases.
• The review could not compare individual interventions because of heterogeneity, and safety balancing measures were reported inconsistently.

Nursing implications

• Pediatric units can use the review to structure approved alarm-reduction work around clear monitoring plans, staff education, nonactionable-alarm measurement, and balancing outcomes. Alarm limits or delays should not be changed outside approved orders and unit protocols, and the review did not identify one superior approach.

Limitations & cautions

• The evidence was dominated by heterogeneous quality-improvement and nonrandomized studies, with only two randomized trials. Intervention effects could not be compared, balancing measures were inconsistent, no pooled effect estimate was available, and methods for systematically reviewing quality-improvement studies are not standardized.
• AI-summarized from the linked source. Review the original article before applying to practice.

Key takeaways

• The review included five studies from four countries and a combined 379 nursing students.
• Three included studies were randomized controlled trials and two used quasi-experimental designs.
• The pooled evidence indicated that serious games had positive effects on CPR knowledge.
• Variation in games, platforms, gamification elements, and study methods limits certainty and supports the need for more robust trials.

Nursing implications

• For nurse educators and preceptors, serious games may be useful as a supplement for CPR knowledge review, especially before simulation or skills validation. The review does not support replacing hands-on practice, objective skill assessment, or the current resuscitation curriculum with game-based learning alone.

Limitations & cautions

• Only five studies and 379 students were included, with substantial variation in the interventions, platforms, gamification features, and methods. The abstract does not provide the pooled effect estimate, durability of learning, psychomotor performance, transfer to real resuscitation, or patient outcomes, so the conclusion should remain limited to CPR knowledge.
• AI-summarized from the linked source. Review the original article before applying to practice.

Key takeaways

• The review included 20 publications spanning guidelines, systematic reviews, evidence summaries, consensus documents, an implementation report, clinical decision resources, and randomized trials.
• The authors synthesized 46 evidence items into 10 prevention domains relevant to perinatal and neonatal intensive care.
• The domains extended across the care continuum, including antenatal preparation, immediate intrapartum and postnatal management, physiologic monitoring, care bundles, and staff education.
• The authors cautioned that implementation should account for the original evidence grade and context as well as local policy, equipment, and staffing constraints.

Nursing implications

• For nurses caring for preterm infants, the review offers a checklist of domains to examine when auditing local IVH-prevention practice, including thermal, oxygenation, hemodynamic, glucose, bundle, and education processes. It should be used as an evidence map, with each proposed change checked against the underlying source, the infant's condition, and the institution's neonatal protocol.

Limitations & cautions

• This was a broad evidence summary that combined different source types and levels of evidence rather than a new meta-analysis of patient outcomes. The abstract does not report the individual recommendations or their grades, and the authors note that differences in policy, equipment, and human resources may limit transfer across neonatal settings.
• AI-summarized from the linked source. Review the original article before applying to practice.

Key takeaways

• Across 16 studies and 24 models, pooled discrimination for post-stroke delirium was an AUC of 0.83 (95% CI 0.81 to 0.85).
• The most common significant predictors were age, NIHSS score, neutrophil-to-lymphocyte ratio, visual impairment, and infection.
• Individual model AUCs ranged from 0.72 to 0.94, with sample sizes from 100 to 14,475.
• PROBAST rated every study at high overall risk of bias, mainly from analysis-domain shortcomings, and clinical utility was rarely tested.

Nursing implications

• For neuro nurses, the recurring predictors (older age, higher NIHSS or stroke severity, signs of infection, and visual impairment) are practical cues to screen more vigilantly for delirium with a validated tool such as CAM-ICU or 4AT and to reinforce non-pharmacologic prevention (reorientation, sleep, early mobility, sensory aids). Because all models carried a high risk of bias, treat any risk score as a prompt for closer assessment, not a substitute for it.

Limitations & cautions

• The review pooled model-development and validation studies of varying design, and PROBAST rated all 16 at high overall risk of bias, so the true performance of these models is uncertain and may vary markedly between settings. Diagnostic criteria for post-stroke delirium differed across studies, calibration was reported in only six, and clinical utility was seldom evaluated; the analysis synthesizes predictors, not proof that acting on them changes outcomes.
• AI-summarized from the linked source. Review the original article before applying to practice.

Key takeaways

• Across 18 studies and 2,952 participants, social and emotional learning was consistently associated with better adaptation, communication, leadership, relationships, and clinical performance.
• Relationship skills and self-management (teamwork, communication, and stress regulation) were the most studied competencies.
• Self-awareness, social awareness, and especially responsible decision-making, important for ethical reasoning, were underexplored.
• Blended learning, simulation, reflective activities, and mentorship emerged as effective strategies aligned with Generation Z learners.

Nursing implications

• For nurses who precept or mentor, the review supports investing in the relational and stress-regulation skills of newer staff through reflective conversations, simulation debriefs, and mentorship rather than focusing only on technical checklists. It also flags responsible decision-making, ethical reasoning under pressure, as an area where formal support is thin, worth attention when onboarding new graduates onto the unit.

Limitations & cautions

• The review combined quasi-experimental, descriptive, qualitative, and mixed-methods studies and reported a narrative synthesis rather than pooled effect sizes, so the associations described are not quantified and cannot establish that social and emotional learning causes better outcomes. Evidence was uneven across competencies, with responsible decision-making and self- and social awareness sparsely studied, and the included research varied in design and quality.
• AI-summarized from the linked source. Review the original article before applying to practice.

Key takeaways

• Across 11 trials and 4,462 adults, more frequent repositioning did not clearly reduce pressure injuries: 2-hourly versus 4-hourly turning showed no significant difference (RR 1.05, 95% CI 0.79 to 1.39).
• The strongest signal came from one ICU trial where wearable sensors with visual repositioning reminders reduced pressure injuries (RR 0.28, 95% CI 0.10 to 0.75; moderate certainty).
• Operating-room micromovement suggested fewer pressure injuries (RR 0.28, 95% CI 0.11 to 0.67), but events were few and certainty was low.
• Most of the evidence was low or very low certainty, and no trials reported quality of life, procedural pain, or patient satisfaction.

Nursing implications

• Keep repositioning as standard care, but recognize the evidence does not strongly favor one turning interval over another, so individualize frequency to skin assessment and risk rather than treating a rigid two-hour rule as proven. Where wearable repositioning-reminder systems are in use, support them, since the one ICU trial testing them showed a reduction. In the OR, micromovement and pressure-redistribution measures are reasonable adjuncts, and be alert that prone patients in the ICU may be at higher risk and need closer skin surveillance.

Limitations & cautions

• Most included trials were small and rated low or very low certainty, so the findings are uncertain and the apparent benefits of sensor reminders and micromovement each rest on limited data. The wearable-sensor result came from a single ICU trial, and no trials reported quality of life, procedural pain, or patient satisfaction. Economic data were sparse, drawn from two older nursing-home evaluations, limiting conclusions about the relative costs of different regimens.
• AI-summarized from the linked source. Review the original article before applying to practice.

Key takeaways

• Tailored education probably reduced the fall rate by about 27% (RaR 0.73, 95% CI 0.56 to 0.94; moderate certainty).
• The same education approach probably reduced the risk of falling (RR 0.61, 95% CI 0.40 to 0.92).
• Service-model changes targeting falls probably cut the acute-setting fall rate (RaR 0.45, 95% CI 0.27 to 0.74).
• Exercise alone, medication optimisation, and general multifactorial programs had uncertain effects consistent with little or no benefit.

Nursing implications

• Make falls teaching specific to the patient by naming their actual risks (sedatives, urgency, line tethering, new weakness) rather than handing over a generic pamphlet, and pull family into that conversation. Reinforce it every shift and after any change, and do not assume an exercise or medication-review checkbox alone protects the patient.

Limitations & cautions

• Even the best-supported interventions carried only moderate-certainty evidence, and the education findings rested on a small number of trials. Hospital populations and how tailored education was delivered varied widely, and most participants were around age 79, so results apply best to older inpatients.
• AI-summarized from the linked source. Review the original article before applying to practice.

Key takeaways

• Across 97 studies, the best MDRO-prevention strategy was a combination, not any single measure.
• Contact precautions plus chlorhexidine bathing was most effective at preventing MDRO acquisition (RR 0.38, 95% CI 0.18 to 0.79).
• Standard plus contact precautions plus environmental cleaning was most effective against MDRO infection (RR 0.04, 95% CI 0.02 to 0.08).
• Mortality and MDRO bacteremia showed no significant benefit, and most studies carried medium-to-high risk of bias.

Nursing implications

• Treat contact precautions as a non-negotiable foundation for MDRO patients rather than relying on hand hygiene alone, and support CHG bathing protocols where ordered, since CHG paired with precautions kept emerging in the most effective combinations. Reinforce environmental cleaning, and know your unit's local resistance profile because the best bundle differed by setting and organism.

Limitations & cautions

• Most included studies were non-randomized and prone to confounding, and most of the RCTs carried medium-to-high risk of bias, so effect estimates should be read cautiously. The strongest combinations varied by outcome, setting, and strain, and hard outcomes like mortality showed no significant effect.
• AI-summarized from the linked source. Review the original article before applying to practice.

Key takeaways

• The framework synthesis reviewed 25 articles linking ED crowding to patient-initiated violence against emergency nurses.
• Crowding was examined across input, throughput, and output stages, alongside staffing factors, rather than as a single metric.
• Patients with severe symptoms triaged to lower-priority categories were a notable high-risk group, partly due to perceptions of injustice about their wait.
• The authors call for accurate, multidimensional crowding assessment and understanding of high-risk patients' emotional state to guide violence prevention.

Nursing implications

• Treat ED crowding as a safety condition, not just a flow problem, and watch for escalating frustration in patients who are visibly unwell but waiting in lower-priority queues. Keep these high-risk patients informed about waits and reassessment, use de-escalation early, and report violence and near-misses so staffing and environmental risks are acted on rather than normalized.

Limitations & cautions

• This is a qualitative framework synthesis of heterogeneous studies, so it organizes contributing factors rather than proving that reducing crowding lowers violence rates. The authors note limited evidence on family members' perspectives, and findings reflect the included literature through March 2024.
• AI-summarized from the linked source. Review the original article before applying to practice.