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A tailored nursing program was associated with fewer falls during chemotherapy for older adults with lymphoma

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (PubMed)Jul 18, 2026

AI-summarized from the linked source. Educational brief, not medical advice.

Brief summary

In a single-center randomized trial of 210 adults aged 65 or older receiving chemotherapy for non-Hodgkin lymphoma, a multifactorial nursing program was associated with fewer falls over 12 weeks than standard oncology nursing (7.1% versus 19.8% among 194 participants who completed follow-up).

What NurseJet pulled from the source

This prospective randomized trial assigned 210 older adults with newly diagnosed or relapsed non-Hodgkin lymphoma to individualized fall-risk assessment plus a multifactorial preventive nursing program or standard oncology nursing. Of 194 participants who completed 12 weeks of follow-up, fall incidence was 7.1% in the intervention group and 19.8% in the control group. The intervention group also had fewer severe injuries, better Timed Up and Go performance, higher chemotherapy completion, and higher quality-of-life scores. Because the study was conducted at one center and reports outcomes among completers, the results support structured fall-prevention assessment without establishing that one protocol will work in every oncology setting.

Why this matters for nurses

Oncology nurses repeatedly assess mobility, neuropathy, anemia, treatment effects, and environmental risks that can change throughout chemotherapy. This trial directly tests a nursing-led approach for a high-risk older population.

Bedside takeaway

A multifactorial nursing program was associated with fewer falls in older adults receiving lymphoma chemotherapy, but the single-center protocol needs local review.

How This Applies in Practice

Use this when: Assessing an older adult's fall risk before or during chemotherapy for non-Hodgkin lymphoma.

On your shift

  • Reassess mobility and treatment-related fall risks at clinically relevant visits and after any fall, near-fall, or functional change.
  • Match prevention measures to the documented risks and communicate new weakness, neuropathy, dizziness, or injury to the oncology team.
Keep in mind: Do not import the study protocol without local review. Follow the oncology fall-prevention pathway, facility policy, and patient-specific provider orders.

Explain this for my unit

Key takeaways

  • The single-center randomized trial enrolled 210 adults aged 65 or older receiving chemotherapy for non-Hodgkin lymphoma.
  • Fall incidence among 194 follow-up completers was 7.1% with the preventive nursing program and 19.8% with standard care.
  • The intervention group also had better functional-mobility, chemotherapy-completion, and quality-of-life outcomes.
  • The 12-week, single-center design and completer analysis limit generalizability.

Practice implications

  • Use the facility's oncology fall-risk process to reassess mobility and treatment-related risks across chemotherapy visits, then individualize prevention measures and document changes. Escalate new weakness, neuropathy, dizziness, falls, or injuries through the oncology team rather than adopting the study protocol without local review.

Limitations & cautions

  • The trial was conducted at one center, followed patients for 12 weeks, and reports results for 194 of 210 enrolled participants who completed follow-up. The abstract does not describe allocation concealment, blinding, or every component of the intervention, and the authors call for multicenter, longer-term validation.
  • AI-summarized from the linked source. Review the original article before applying to practice.

Citations

Exact source links

Public citations are filtered to exact credible source pages. Homepage-only or invalid links stay in admin review and are not shown here.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (PubMed)

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (PubMed). A clinical study on fall risk assessment and preventive nursing in older adults with non-Hodgkin's lymphoma undergoing chemotherapy-a randomized controlled trial.

Open original source

https://pubmed.ncbi.nlm.nih.gov/42470465/

Professional education only

This summary does not replace clinical judgment, facility policy, provider orders, or official guidelines. Verify practice changes against the original source and local protocol.

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