Research ArticleResearchPatient EducationInfection Control

Virtual reality hypnosis eased anxiety during protective isolation in a small trial

Supportive care in cancer (PubMed)Aug 24, 2026

AI-summarized from the linked source. Educational brief, not medical advice.

Brief summary

A small randomized trial found three daily virtual reality hypnosis sessions reduced anxiety more than a control activity among neutropenic adults in protective isolation, while pain scores remained low and similar.

What NurseJet pulled from the source

Sixty adults entering protective isolation were randomized to a 20-minute virtual reality hypnosis session or a control activity for three days. Anxiety questionnaires were scorable for 58 participants on day one, 40 on day two, and 30 on day three; mean anxiety reductions were 6.4 points with virtual reality hypnosis versus 1.9 points with control.

Why this matters for nurses

Oncology nurses address the emotional burden of prolonged isolation while preserving infection-prevention precautions. Virtual reality hypnosis may offer a structured nonpharmacologic support option for interested, appropriate patients.

Bedside takeaway

VR hypnosis may ease isolation-related anxiety when acceptable to the patient and compatible with infection-prevention precautions.

How This Applies in Practice

Use this when: Supporting an adult with neutropenia who is experiencing anxiety during protective isolation.

On your shift

Assess anxiety, orientation, nausea, dizziness, visual or hearing needs, and willingness before offering the approved device.
Prepare and handle the equipment within the unit's protective-isolation and device-cleaning workflow.
Reassess anxiety and tolerance after the session and communicate persistent or worsening distress to the care team.

Keep in mind: The evidence comes from one small open-label trial and does not replace comprehensive anxiety care. Follow infection-control policy, facility protocol, and provider orders.

Key takeaways

The open-label single-center trial randomized 60 neutropenic adults entering protective isolation.
Anxiety decreased more after virtual reality hypnosis than after the control activity.
Pain ratings were below 2 and did not differ between groups.
Scorable anxiety data fell from 58 participants on day one to 30 on day three.

Practice implications

Assess anxiety, symptoms, device tolerance, and contraindications before use; maintain all protective-isolation precautions during the session; and reassess distress afterward while continuing the broader supportive-care plan.

Limitations & cautions

The study was open label, single center, and small. The number of participants with scorable anxiety data declined across the three days, pain was minimal at baseline, and the results do not establish durability or generalizability.
AI-summarized from the linked source. Review the original article before applying to practice.

Citations

Exact source links

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Supportive care in cancer (PubMed)

Supportive care in cancer (PubMed). Virtual reality hypnosis during protective isolation: a parallel group randomized trial.

Open original source

https://pubmed.ncbi.nlm.nih.gov/42635826/

Professional education only

This summary does not replace clinical judgment, facility policy, provider orders, or official guidelines. Verify practice changes against the original source and local protocol.

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Trauma, violence & abuse (PubMed)Oct 17, 2026Systematic Review

A systematic review and meta-analysis of 20 emergency department studies encompassing 7,498 women found intimate partner violence was associated with a three-fold increased risk of suicide attempt, with psychological violence showing a stronger association than physical violence.

Emergency PsychAI summaryReview source

Systematic ReviewResearchWorkflowQuality ImprovementAI summary · original source linked below

Women experiencing intimate partner violence (IPV) and acute suicidality frequently seek medical evaluation in emergency departments (EDs), but the intersection between these two acute presentations is often overlooked during fast-paced triage. This systematic review, meta-analysis, and narrative synthesis synthesized 20 ED-based studies comprising 7,498 women across three global databases. Investigators used random-effects models and evaluated study quality with the Joanna Briggs Institute (JBI) checklist. Overall, 22% (95% CI: 11%–36%) of women presenting to the ED for suicide-related care had a history of physical IPV, while 13% (95% CI: 8%–18%) of women with known IPV histories reported active suicidality. A history of IPV was associated with a three-fold increase in the risk of suicide attempt (risk ratio [RR] 3.00; 95% CI: 1.39–6.47). Notably, psychological IPV demonstrated a stronger association with suicide risk (RR 3.23; 95% CI: 1.68–6.19) than physical IPV alone (RR 2.00; 95% CI: 1.26–3.17).

Key takeaways

Systematic review synthesized 20 emergency department studies encompassing 7,498 women.
Nearly 1 in 4 women (22%; 95% CI: 11%–36%) presenting to the ED with suicidality had experienced physical IPV.
IPV was associated with a three-fold higher risk of suicide attempt (RR 3.00; 95% CI: 1.39–6.47).
Psychological IPV showed a higher risk ratio for suicide attempts (RR 3.23; 95% CI: 1.68–6.19) than physical IPV (RR 2.00; 95% CI: 1.26–3.17).

Why this matters on shift

Emergency nurses are the primary healthcare professionals conducting universal triage, suicide risk screening (e.g., C-SSRS), and domestic violence assessments. Recognizing that nearly one-quarter of suicidal female presentations co-occur with IPV—and that non-physical, psychological abuse carries an even higher relative risk for suicide attempt—demands that ED nursing assessments integrate trauma-informed safety planning rather than treating suicidality and relationship violence in isolation.

Bedside takeaway

In an ED meta-analysis of 7,498 women, intimate partner violence tripled suicide attempt risk (RR 3.00), with psychological IPV (RR 3.23) linked more strongly than physical IPV (RR 2.00).

Nursing implications

Conduct routine IPV and suicide screenings privately away from companions or visitors, assess for emotional and psychological coercion even when physical injury is absent, and connect patients showing combined risk immediately to hospital social work, victim advocacy, and safe crisis intervention pathways.

Limitations & cautions

High between-study heterogeneity across meta-analytic models (I² > 75%); high risk of bias identified in half of the included primary studies; relied largely on cross-sectional self-reported survey measures.
AI-summarized from the linked source. Review the original article before applying to practice.

Citations · exact source links

Trauma, violence & abuse (PubMed). Intimate Partner Violence and Suicide Risk among Women Presenting to Emergency Departments: A Systematic Review, Meta-Analysis, and Narrative Synthesis.

Open original sourceFull brief

AI-summarized from the linked source. Review the original article before applying to practice.

Journal of clinical oncology (PubMed)Sep 16, 2026Research Article

In the MATCH comparative effectiveness trial of 587 cancer survivors, both mindfulness-based cancer recovery and Tai Chi/Qigong significantly reduced post-treatment fatigue and pain interference compared to controls, with Tai Chi also significantly improving sleep quality.

Oncology Med-SurgAI summaryReview source

Research ArticleResearchPatient EducationAI summary · original source linked below

Cancer survivors frequently experience a distressing co-occurring symptom cluster of persistent fatigue, sleep disruption, and chronic pain following primary therapy. The MATCH trial (Mindfulness and Tai Chi for Cancer Health) was a partially randomized patient-preference comparative effectiveness trial evaluating Mindfulness-Based Cancer Recovery (MBCR) and Tai Chi/Qigong (TCQ) in distressed cancer survivors across diverse cancer diagnoses and stages. Enrolled participants (N = 587; mean age 60.7 years) either chose an intervention or underwent randomization to MBCR or TCQ, followed by secondary randomization to immediate intervention or waitlist control. At post-intervention, both MBCR and TCQ produced statistically significant reductions in fatigue compared to waitlist controls, with mean improvements of 3.66 points (P = .036) and 3.42 points (P = .043), respectively. Pain interference improved by more than 1 point in both active groups (MBCR: P = .029; TCQ: P = .002). TCQ also yielded a statistically significant 1.9-point improvement on the sleep quality scale after multivariable adjustment (P = .004). Clinical outcomes did not differ between MBCR and TCQ, and participant preference status did not affect intervention efficacy.

Key takeaways

Partially randomized patient-preference trial enrolled 587 distressed cancer survivors across multiple tumor types and disease stages.
Both mindfulness (MBCR) and movement-based Tai Chi (TCQ) produced statistically significant improvements in cancer-related fatigue (P = .036 and P = .043).
Both interventions achieved meaningful reductions of greater than 1 point in chronic pain interference (P = .029 and P = .002).
Tai Chi uniquely achieved a statistically significant 1.9-point improvement in overall sleep quality scale scores (P = .004).

Why this matters on shift

Oncology and outpatient clinic nurses frequently support cancer survivors struggling with debilitating symptom clusters that persist long after chemotherapy and radiation end. Confirming that both structured mindfulness and Tai Chi offer comparable, evidence-based relief for fatigue and pain interference equips nurses to guide patients toward integrative therapies matching their physical mobility and lifestyle preferences.

Bedside takeaway

In a 587-patient trial of cancer survivors, both mindfulness (MBCR) and tai chi (TCQ) significantly reduced post-treatment fatigue (p=0.036 and p=0.043) and pain interference (p=0.029 and p=0.002), with tai chi also improving sleep quality (p=0.004).

Nursing implications

Screen cancer survivors routinely for clustered symptoms of fatigue, pain, and insomnia, and discuss evidence-backed integrative referrals such as mindfulness-based recovery or Tai Chi as non-pharmacological adjuncts to symptom management.

Limitations & cautions

Partially randomized design allowed patient preference selection; waitlist comparison group rather than active sham control; symptom endpoints relied on patient-reported validated scales.
AI-summarized from the linked source. Review the original article before applying to practice.

Citations · exact source links

Journal of clinical oncology (PubMed). Mindfulness and Tai Chi for Sleep, Fatigue, and Pain in Distressed People After Cancer Treatment: A Partially Randomized Patient-Preference Comparative Effectiveness Trial.

Open original sourceFull brief

AI-summarized from the linked source. Review the original article before applying to practice.

Intensive care medicine (PubMed)Oct 1, 2026Research Article

The 18-center TRANSPORT randomized trial of 187 cancer patients with septic shock found that a liberal transfusion strategy (Hb threshold 9.0 g/dL) did not improve 12-hour lactate clearance (52% vs 50%) or 28-day survival over a restrictive strategy (Hb threshold 7.0 g/dL), but increased thrombotic events from 1% to 13%.

ICU OncologyAI summaryReview source

Research ArticleResearchMedication SafetyQuality ImprovementAI summary · original source linked below

Septic shock carries high mortality among oncology patients, in whom severe anemia frequently prompts clinician concern regarding systemic tissue hypoxia. The multicenter TRANSPORT superiority randomized trial, conducted across 18 intensive care units in France, evaluated whether an early liberal red blood cell transfusion threshold (hemoglobin target 9.0 g/dL, n=93) improved tissue perfusion compared to a restrictive threshold (hemoglobin target 7.0 g/dL, n=94) during the initial 48 hours of resuscitation in adult cancer patients with septic shock (baseline lactate > 2.0 mmol/L and Hb < 9.0 g/dL). The trial was stopped prematurely for safety concerns after enrolling 187 of a planned 260 patients. Twelve-hour lactate reduction (normalization <= 2.0 mmol/L or >= 30% decrease) showed no difference between arms (52% liberal vs 50% restrictive; odds ratio 1.07; 95% CI 0.60 to 1.90; P = 0.82). Arterial or venous thrombotic complications occurred significantly more often in the liberal group (13% vs 1%; P = 0.001), while 28-day mortality remained comparable (46% liberal vs 53% restrictive; P = 0.34).

Key takeaways

Multicenter randomized trial in 18 French ICUs evaluated transfusion thresholds during initial 48 hours of septic shock in cancer patients.
Trial halted prematurely at 187 patients due to safety imbalances between study arms.
Liberal transfusion (Hb < 9.0 g/dL) failed to improve 12-hour lactate clearance (52% vs 50%, P = 0.82) or 28-day mortality (46% vs 53%, P = 0.34).
Liberal transfusion was associated with a marked increase in arterial and venous thrombotic events (13% vs 1%, P = 0.001).

Why this matters on shift

Bedside critical care nurses frequently administer blood transfusions in septic shock and monitor for complications. These findings reinforce that higher hemoglobin targets do not accelerate shock resolution even in high-risk oncology patients, and alert nurses to the substantial thrombotic hazard of unneeded liberal transfusions.

Bedside takeaway

In cancer patients with septic shock, liberal transfusion (Hb <9 g/dL) did not improve lactate clearance or 28-day survival over restrictive transfusion (Hb <7 g/dL) but raised thrombotic complications from 1% to 13%.

Nursing implications

Adhere strictly to restrictive transfusion thresholds (hemoglobin < 7.0 g/dL) during septic shock resuscitation unless provider orders or institutional protocol dictate otherwise, and maintain heightened surveillance for deep vein thrombosis or arterial occlusion if liberal transfusions are administered.

Limitations & cautions

Premature termination resulted in underpowered final sample size (187 enrolled of 260 planned); conducted exclusively within French intensive care units; limited to adult hematologic and solid oncology patients.
AI-summarized from the linked source. Review the original article before applying to practice.

Citations · exact source links

Intensive care medicine (PubMed). Early red blood cell transfusion strategy in septic shock among patients with cancer: the TRANSPORT randomized controlled trial.

Open original sourceFull brief

AI-summarized from the linked source. Review the original article before applying to practice.

How This Applies in Practice

Key takeaways

Practice implications

Limitations & cautions

Exact source links

More updates for this clinical area

Meta-analysis of 20 emergency department studies links intimate partner violence to three-fold higher suicide attempt risk

MATCH trial of 587 cancer survivors shows mindfulness and tai chi significantly alleviate post-treatment fatigue and pain interference

TRANSPORT multicenter trial in cancer patients with septic shock finds liberal transfusion offers no lactate or survival benefit but increases thrombosis