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Nearly 1 in 5 confirmed heart attacks arrived without chest symptoms, more often in patients with impaired function or consciousness

Journal of Emergency Nursing (PubMed)Jun 30, 2026

AI-summarized from the linked source. Educational brief, not medical advice.

Brief summary

In a retrospective cohort of 1076 adults aged 40 or older with acute myocardial infarction at a Taiwan teaching hospital, 19% presented without chest-related symptoms, and reduced level of consciousness and greater functional dependence were each independently linked to these atypical presentations.

What NurseJet pulled from the source

This retrospective cohort study used electronic health record data from a regional teaching hospital in Taiwan, including 1076 adults aged 40 years or older diagnosed with acute myocardial infarction between 2016 and 2023. Presentations were classified as typical (chest pain or chest tightness) or atypical (absence of chest-related symptoms). Among the 1076 patients, 19.0% presented without any chest-related symptoms. Patients with atypical presentations were older, had lower body mass index, greater dependence in activities of daily living, and lower Glasgow Coma Scale scores. In multivariable logistic regression, reduced level of consciousness (odds ratio 4.93; 95% CI 2.41 to 10.05; P < .001) and greater functional dependence (odds ratio 1.10; 95% CI 1.06 to 1.15; P < .001) were each independently associated with atypical presentation.

Why this matters for nurses

Emergency nurses are often the first to size up a patient at triage, and chest pain is widely treated as the signature of a heart attack. This study may matter for nurses because nearly one in five confirmed myocardial infarctions arrived without chest symptoms, and the patients most likely to present atypically were those with cognitive or functional impairment who can least advocate for themselves.

Bedside takeaway

Be aware that in this cohort about 1 in 5 confirmed heart attacks came without chest symptoms, and atypical presentation was more likely in patients with reduced consciousness or greater functional dependence.

Explain this for my unit

Key takeaways

  • Among 1076 adults aged 40 or older with acute myocardial infarction, 19.0% presented without any chest-related symptoms.
  • Reduced level of consciousness was independently associated with atypical presentation (odds ratio 4.93; 95% CI 2.41 to 10.05; P < .001).
  • Greater functional dependence in activities of daily living was also independently associated (odds ratio 1.10; 95% CI 1.06 to 1.15; P < .001).
  • Patients with atypical presentations tended to be older with lower body mass index and lower Glasgow Coma Scale scores.

Practice implications

  • For emergency nurses, the findings suggest a heart attack cannot be ruled out on the absence of chest pain alone, especially in older adults or those with reduced consciousness or high dependence in activities of daily living. Folding functional status and Glasgow Coma Scale into the triage picture, and keeping a lower threshold for cardiac workup in impaired patients, may help catch atypical presentations earlier.

Limitations & cautions

  • This was a single-center retrospective cohort at one regional teaching hospital in Taiwan, drawing on electronic health record data from 2016 to 2023, so practice and documentation patterns may not generalize elsewhere. The observational design shows association, not causation, and only patients already diagnosed with acute myocardial infarction were included, so the study cannot speak to how often atypical presentations are missed entirely.
  • AI-summarized from the linked source. Review the original article before applying to practice.

Citations

Exact source links

Public citations are filtered to exact credible source pages. Homepage-only or invalid links stay in admin review and are not shown here.

Journal of Emergency Nursing (PubMed)

Journal of Emergency Nursing (PubMed). Emergency Nursing Recognition of Atypical Acute Myocardial Infarction: Associations With Functional Status and Level of Consciousness-A Retrospective Cohort Study.

Open original source

https://pubmed.ncbi.nlm.nih.gov/42377288/

Professional education only

This summary does not replace clinical judgment, facility policy, provider orders, or official guidelines. Verify practice changes against the original source and local protocol.

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